CFD of Aneurysms
CFD to predict rupture risk in intracranial aneurysms
Overview
My undergraduate dissertation, Computational Fluid Dynamics for Intracranial Aneurysms in Clinical Settings, was conducted under the supervision of Dr. Amir Keshmiri and is currently pending publication in Scientific Reports.
Oscillatory Shear Index (OSI) distributions for Patient #2 in the untreated case, shown across four different simulation views.
Results
- Achieved a final grade of 91% for the dissertation.
- Awarded a grade of 100% for the accompanying poster.
- Successfully segmented patient-specific intracranial aneurysm geometries from medical imaging data.
- Developed and validated high-fidelity CFD meshes to capture aneurysmal blood flow.
- Simulations in STAR-CCM+ demonstrated distinct haemodynamic responses under different treatment strategies:
- Endovascular coiling reduced flow velocity but in some cases left regions of residual circulation.
- Flow-diverting stents provided greater reduction in inflow jet momentum, lowering wall shear stress and oscillatory shear index across the aneurysm dome.
- Quantitative haemodynamic analysis showed that elevated OSI and WSS gradients correlated strongly with rupture-prone regions, in line with published clinical literature.
- The study presented a proof-of-concept for employing patient-specific CFD as a clinical decision-support tool in endovascular treatment planning.